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Prednisolone Vs Pentoxifylline


The benefit of their combination is unknown.Objective: To determine whether the addition of pentoxifylline to prednisolone is more effective than prednisolone alone.The risk of hepatorenal syndrome was decreased at 1 month in the combination therapy group as compared with the placebo group (3.Prednisolone with vs without pentoxifylline and survival of patients with severe alcoholic hepatitis: a randomized clinical trial.Mathurin P, Louvet A, Duhamel A, et al.Pentoxifylline versus prednisolone for severe alcoholic hepatitis: a randomized controlled trial.Patients were treated with either prednisolone 40 mg per day or pentoxifylline 1200 mg per day for 4 weeks.To determine whether the addition of pentoxifylline to prednisolone is more effective than prednisolone alone.Design, setting, and participants: Multicenter, randomized, double-blind clinical trial conducted between.The authors reported prednisolone vs pentoxifylline a lower survival with pentoxifylline as compared to prednisolone both at 4 weeks (75.In the pentoxifylline-prednisolone group, definite withdrawal was related to infection (2 cases) and the patient’s decision (1 case) Prednisolone vs.Overall, there were 82 deaths in the cohort at 6 months -- 40 in the pentoxifylline-prednisolone group and 42 in the placebo-prednisolone group.The proportion of patients who had a Lille model.Importance: Prednisolone or pentoxifylline is recommended for severe alcoholic hepatitis, a life-threatening disease.The authors concluded that pentoxifylline is less effective than prednisolone At day 7, the Lille score was significantly lower in the prednisolone group (n = 58) than in the pentoxifylline group (n = 59) (0.De BK, Gangopadhyay S, Dutta D, et al.Prednisolone with vs without pentoxifylline and survival of patients with severe alcoholic hepatitis: a randomized clinical trial prednisolone vs pentoxifylline Prednisolone or pentoxifylline is recommended for severe alcoholic hepatitis, a life-threatening disease.The benefit of their combination is unknown.Multicenter, randomized, double-blind clinical trial conducted between December 2007.World J Gastroenterol 2009 15: 1613-9.Prednisolone and pentoxifylline are both recommended for the treatment of severe alcoholic hepatitis, but uncertainty about their benefit persists.007), but this difference did not remain significant.

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prednisolone vs pentoxifylline

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